Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised equipment may provide enormous benefits in terms of development times and costs.

Researchers in Barcelona investigate the effect of additives on the effectiveness of cisplatin, a chemotherapy medication, using the CMS196 for cryo-fluorescence miscroscopy.

Researchers at the University of Warwick use the Linkam BCS196 to work at the interface of the organic and polymer chemistries with the life sciences, making use of modern polymer and organic methods to synthesise nano materials for various applications, including regenerative medicine, infectious disease and biotechnology.

White Oak Conservation Centre in Florida uses the BCS196 for IVF research, taking them closer to the goal of one day transporting genetic material collected from wild animals to be introduced into captive populations, enhancing genetic diversity.

Researchers at the University of Leeds are looking at how Protein crystallization is affected by changing the cooling rate.