Freeze Drying Training Course

We are pleased to be involved with the Freeze Drying Training Course ‘Lyophilisation: Practical Applications Utilising Latest Equipment’ at the Hooke College of Applied Sciences, running from 3rd-5th November.

This course covers aspects of freeze drying as it relates to the pharmaceutical, biological and food industries. These topics will first be discussed in a classroom setting and then put into practise in an onsite laboratory. Attendees will get hands-on experience with the Linkam FDCS196 freeze-drying cryo-stage.

Details and registration

The Linkam FDCS196 freeze drying system provides the ability to quickly and accurately determine collapse and eutectic temperature and intricately investigate freeze dried structure of complex samples.

Linkam Scientific introduce students to the CMS196 cryo-CLEM stage at the Francis Crick Institute

Towards the end of September we attended the UK’s first Correlative Light and Electron Microscopy (CLEM) interactive workshop. This was held at the prestigious Francis Crick Institute, in London, and will take place in alternate years with the European EMBO CLEM course in Bristol.

The course was fully booked with eight participants from eight different institutes in the UK working in pairs throughout the week to learn different CLEM workflows. The Linkam CMS196 Cryo-Correlative stage was used during the workshop so students could get practical experience of the system and see how it fits into the Cryo-CLEM workflow.

Above is a picture of mouse embryonic fibroblast (MEF) cells, prepared by PhD student Patricia Goggin and captured by Linkam's Michael Schwertner during the ‘correlative cryo-fluorescence leading to cryo-electron tomography or cryo soft x-ray tomography’ practical. This cryofluorescence image shows the cell nuclei in blue, mitochondria in green and filamentous actin in red. 

We had a great time showing off some of the features of our cyro-CLEM stage whilst also continuing to learn about some of its applications, and our thanks go to everyone involved, especially Dr Marie-Charlotte Domart, Dr Raffa Carzaniga, Dr Lucy Collinson and Dr Paul Verkade.

Freeze Drying Webinar

On Thursday 1st October Linkam distributors The McCrone Group are running a free webinar on 'Thermal Characterization as Part of an Empirical Process for Developing Optimized Formulations and Lyophilization Cycles'.

The Webinar, presented by Dr Jeff Schwegman and McCrone technical sales representative Ruben Neiblas, introduces a well-defined process for taking an empirical approach to designing formulations, and the lyophilization cycles used to dry them.

Details and registration

The webinar preludes a course entitled ‘Lyophilization: Practical Applications Utilizing Latest Equipment’, featuring the Linkam FDCS196 freeze-drying cryo stage. This will take place from the 3rd-5th November.

The Linkam FDCS196 freeze drying system provides the ability to quickly and accurately determine collapse and eutectic temperature and intricately investigate freeze dried structure of complex samples.

Linkam supporting Correlative Light and Electron Microscopy Workshop at Francis Crick Institute

Linkam will be supporting the first UK hands-on workshop on ‘Correlative Light and Electron Microscopy', being held at the Francis Crick Institute in London from September 21st to 25th.

The workshop is organised by Raffa Carzaniga, Lucy Collinson and Paul Verkade, and will take place in alternate years with the European EMBO CLEM course in Bristol (next course in July 2016), enabling us to train more of the UK community in a wide range of CLEM techniques. The workshop will include detailed hands-on tutorials for 8-10 participants organised into groups of 2 people per tutor to maximise contact time, covering high pressure freezing and freeze substitution; preservation of fluorescence in-resin for integrated microscopy; plunge freezing, cryofluorescence and cryoEM; Tokuyasu cryosectioning and immunolabelling for correlative experiments; and 3D CLEM using Serial Block Face SEM.

The Linkam CMS196 Cryo Correlative stage will be used during the workshop so students will be able to get practical experience of the system and see how it fits into the Cryo-CLEM workflow.