Deciphering the role of amphiphilic polymer combinations in the formation of ternary griseofulvin amorphous solid dispersions using Linkam's THMS600

Researchers at Aristotle University of Thessaloniki, NatPro-AUTH, CIRI-AUTH, in Greece used Linkam’s THMS600 to investigate how different combinations of amphiphilic polymers influence the formation, physical stability, and dissolution performance of ternary amorphous solid dispersions (ASDs) of griseofulvin (GRF), a poorly soluble drug with a strong tendency to recrystallise.

Webinar: From Ancient Relics to Life on Mars: Temperature-Controlled Experiments for Materials Characterisation

In advance of the Mars landing on 18 February 2021, members of the Analytical Chemistry group at Universidad del País Vasco / Euskal Herriko Unibertsitatea (University of the Basque Country) in Leioa, Spain presented their research on how temperature controlled experiments (including Raman spectroscopy, X-ray fluorescence and XRD analysis) can be used to characterise geological materials ranging from historical artefacts from the Roman empire to regolith samples from Mars.

The importance of being small: miniaturisation of freeze drying equipment

Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised equipment may provide enormous benefits in terms of development times and costs.