In this customer insight, Dr Maria Harikiolaki, Principal Beamline Scientist at Diamond Light Source describes how Linkam is responsive to their requirements and maintains a consistent degree of excellence in the products provided.
Unravelling the complexities of freeze-drying pharmaceuticals with advanced microscopy techniques
Linkam’s FDCS196 was used by researchers at the UK’s National Institute for Biological Standards and Control (NIBSC) and the University of Strathclyde to predict freeze-drying conditions for liposome-cryoprotectant mixtures (drug delivery systems), using light microscopy with a cryostage.
The importance of being small: miniaturisation of freeze drying equipment
Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised equipment may provide enormous benefits in terms of development times and costs.
Researchers use Linkam stages to investigate how temperature-controlled microscopy enhances research of chemical processes in polar ice
The Effect of Supercooling on Cryopreservation of Cells using Linkam’s FDCS196
Intracellular segregation processes in the endocytic system
Improved suppression of cancerous cells by regulating the toxicity of chemotherapy medication using Linkam’s CMS196.
Exploring Protein-Inspired Ice Recrystallisation Inhibition using Linkam’s BCS196
Researchers at the University of Warwick use the Linkam BCS196 to work at the interface of the organic and polymer chemistries with the life sciences, making use of modern polymer and organic methods to synthesise nano materials for various applications, including regenerative medicine, infectious disease and biotechnology.