Michelle Coffie 19 May 2020 Case Study Investigating Protein Crystallisation Growth Using the LTS Stage Series. Michelle Coffie 19 May 2020 Case Study Linkam’s LTS420 shown above. Researchers at the University of Leeds, UK looked at how protein crystallisation is affected by changing the cooling rate using a Linkam LTS350 stage (now replaced by the LTS420).Find out more here.