Researchers at Aristotle University of Thessaloniki, NatPro-AUTH, CIRI-AUTH, in Greece used Linkam’s THMS600 to investigate how different combinations of amphiphilic polymers influence the formation, physical stability, and dissolution performance of ternary amorphous solid dispersions (ASDs) of griseofulvin (GRF), a poorly soluble drug with a strong tendency to recrystallise.
Studying a New Polymorph of Metacetamol using Linkam’s FTIR600
Investigating drug-polymer interactions using optical DSC
Researchers from the University of Hertfordshire’s School of Life and Medical Sciences collaborated with Linkam to provide an in-depth analysis into how the optical DSC450 and TASC can be used to characterise drug-polymer-excipient systems for pharmaceutical applications. Read the full case study here.
A Novel Thermal Microscopic Imaging Tool for Rapid Pre-Formulation Screening of Solid Dispersions
Studying Phase Transitions in Pharmaceuticals using Linkam’s DSC450 in combination with TASC.
Polymorphism in pharmaceutical solids has great implications on both the processing and the performance of solid pharmaceutical products. This app note details work from the School of Pharmacy at UCL using TASC with our DSC450 to characterise polymorphic transitions in the pharmaceutical active compound flufenamic acid .