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The technique of cryogenic fluorescence microscopy (cryo-FLM) is rapidly emerging as the foundation of modern cryomicroscopy. The convergence of advancements in drift-stable imaging and automated sample preparation is establishing cryo-FLM as a central driver of workflow quality.
In addition to its use as a targeting tool for cryo-electron microscopy (cryo-EM), cryo-FLM also demonstrates a direct influence on the success of downstream electron-based techniques. As a result, the cryogenic imaging pipeline can now be reframed from the perspective of cryo-FLM. Innovations in drift-stabilised flouresecence imaging, and blot-free sample preparation, are transforming what cryo-EM can achieve to end users.
Find out how Linkam’s CMS196V4 and CryoGenium can enhance your cryomicrosopy research here.*
*Article reproduced from February 2026 issue of PHOTONICS SPECTRA © Laurin Publishing.
Linkam CMS196 V4 shown above.