3D printing pharmaceutical products opens the door to an exciting world of individually tailored drugs, unique for each patient. In this paper the drying process of single and multi-layered printed materials was monitored using the Linkam Imaging Station, monitoring changes in pore size as the 3D printed paracetamol was dried.
HFS600 stage shown on the Linkam Imaging Station
Researchers at the University of Liverpool used a Linkam TST350 stage (now replaced by the LTS420) for this study.
LTS420 shown above
THMS600 and DSC450 shown above
Find out here about how hot stage microscopy (HSM) and Differential Scanning Calorimetry (DSC) can be used for pharmaceutical applications.
Choose Linkam’s THMS600, for hot stage microscopy, or our DSC450 for optical differential scanning microscopy.
Kumar, A., Singh, P. & Nanda, A. Hot stage microscopy and its applications in pharmaceutical characterization. Appl. Microsc. 50, 12 (2020). DOI: 10.1186/s42649-020-00032-9
Using one of Linkam’s Peltier stages, research performed hot stage microscopy measurements on inorganic salts for pharmaceutical applications.
Read the full paper here (access required).
In this work, researchers used Linkam’s LTS350 (now replaced by the LTS420) stage to characterise the physiochemical properties of a pharmaceutical solid compound in four different forms (anhydrous polymorphs (Forms I and II) and two monohydrates (Forms III and IV)) to evaluate its suitability for pharmaceutical development.
Read the full paper here (access required).
LTS420 shown above