Discover the process of characterisation of the mechanical properties of samples through mechanical force testing using optical hot stage microscopy. This includes everything from tensile strain testing to 3-point bending experiments, with temperature and environmental control.
Cryo correlative light electron microscopy (cryo-CLEM) is a powerful technique that combines the advantages of cryo-fluorescence microscopy and cryo-electron microscopy to study biological samples in their near-native state. Cryo-CLEM allows researchers to identify and locate specific molecules of interest within the ultrastructure of cells or tissues, revealing the molecular mechanisms of life.
What is hot stage microscopy? A technique that uses temperature control systems to study materials at high temperatures and observe thermal phenomena.
At Linkam we get really excited about new technology. This week we’ve been trying out ChatGPT, the new AI everyone is talking about, and decided to interview it about Linkam.
Cryo-EM, cryo-tomography, Single Particle Tomography (SPT) and cryo-CLEM (Correlative Light and Electron Microscopy) have become standard tools for the investigation of protein 3D structures, cellular structures and more in the last decade. Despite the progress with cryo-EM instruments and automated sample loading and imaging the routine preparation of cryo-samples can be challenging.
Read how researchers at Huddersfield University used the Linkam DSC450 that combines Differential Scanning Calorimetry with Optical observation to gain additional insights into the properties of different materials.
Wearable electronics and sensors are becoming increasingly popular and will play an important role in the future of smart technology including those within sport and medical applications.
New research indicates hot-melt extrusion produces predictable, high drug loading amorphous solid dispersions.
Humidity plays a role in the functioning and lifetime of many products, from foods to pharmaceuticals and from polymers to metals. It can significantly impact the properties of a material, such as its cosmetic surface, and mechanical and chemical properties.
The McCrone Group's Hooke College of Applied Sciences recently hosted a webinar looking at multi-tiered microscopy analysis for wound care products, such as bandages.
Freeze drying has emerged as an important technique for the storage and transportation of pharmaceutical compounds. It has also been widely used in the formulation and development of diagnostic reagents, including those for COVID-19 testing. In this work, researchers use Linkam’s FDCS196 to look at how freeze drying can be used to characterise the antipsychotic drug, Risperidone, and pave the way for new transdermal drug delivery systems.
Scientists and historians have devoted great time and effort into understanding how historical and archaeological artifacts degrade and what can be done to better preserve them. Whether viewing a fifteenth century oil painting, a handwritten document on parchment from ancient Rome, or clothing and tools from prehistoric times, researchers have investigated the preservation process in order to ensure these items are not lost forever.
A recent study undertaken at Rovira i Virgili University in Tarragona, Spain, reveals that biolabeling through luminescence thermometry has the potential to detect cancer cells at an early stage of development, just by monitoring the temperature rise in the body, due to accelerated metabolic activities in abnormal cells.
Date: Thursday 19th November 2020. Time: 7:00 PM - 7:45 PM GMT
In this free webinar, Linkam’s Application Specialist Robert joins Glenn from McCrone to present an overview of our modular force testing system, the MFS. Gain a better understanding of microscopic and thermo-mechanical properties on a wide variety of samples and applications. Free registration here.
A team of scientists set out to understand how and why lasers trigger crystallisation and how changes made to the properties of the laser could influence which crystal form is generated. Researchers working with Professor Klaas Wynne of The School of Chemistry at the University of Glasgow have used Linkam’s THMS600 temperature-controlled stage to explore phase transitions in mixed liquid systems and laser-induced nucleation.
Fluid inclusions are microscopic bubbles of liquids and gases that are trapped during the formation of crystals in various geological environments.