Researchers use a Linkam probe stage, the HFS600E-PB4 to study the relationship between vertical interfaces and dielectric properties in thin nanocomposite films.
Submillisecond-response nematic liquid crystals for augmented reality displays
Researchers use Linkam’s Liquid Crystal System to study nematic liquid crystals for augmented reality displays.
Electrically driven three-dimensional solitary waves as director bullets in nematic liquid crystals
Researchers use Linkam’s Liquid Crystal System to study nematic liquid crystals.
Multi-level chirality in liquid crystals formed by achiral molecules
Researchers use Linkam’s Liquid Crystal System to study the chirality of liquid crystals.
An Experimental Study of the Formation of Talc through CaMg(CO3)2–SiO2–H2O Interaction at 100–200∘C and Vapor-Saturation Pressures using Linkam’s CAP500
Researchers used Linkam’s CAP500 (shown above) with fused silica capillaries to study the formation of talc, observing the process using techniques including Raman spectroscopy and X-ray diffraction.
Access the research here.
Wan, Ye, et al. "An Experimental Study of the Formation of Talc through CaMg (CO3) 2–SiO2–H2O Interaction at 100–200 C and Vapor-Saturation Pressures." Geofluids 2017 (2017).
Study of SO2/water and NO/water/salt systems from 25 to 150 °C using fused silica capillaries, batch autoclave and Raman microspectrometry using Linkam’s CAP500
Researchers used the Linkam CAP500 to study the thermodynamic behaviour of CO2 capture systems, using fused silica capillaries under Raman spectroscopy.
Using Linkam’s mechanical testing system to investigate the reductive dissolution of supergrowth carbon nanotubes for tougher nanocomposites by reactive coagulation spinning
Researchers used Linkam’s TST350, now MFS to image and measure the tensile properties of nanocomposite samples synthesised by coagulation spinning using carbon nanotubes.
X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser
Researchers used the Linkam CMS196 for imaging cryopreserved human prostate cancer cells with X-ray tomography.
Imaging endosomes and autophagosomes in whole mammalian cells using correlative cryo-fluorescence and cryo-soft X-ray microscopy (cryo-CLXM)
Imaging of Vitrified Biological Specimens by Confocal Cryo Fluorescence Microscopy and Cryo FIB /SEM Tomography
CMS196V4 shown above
Researchers used Linkam’s CMS196 as part of a Confocal Cryo Fluorescence Microscopy setup to image vitrified biological samples.
Access the research here.
Schertel, Andreas, et al. "Imaging of Vitrified Biological Specimens by Confocal Cryo Fluorescence Microscopy and Cryo FIB/SEM Tomography." European Microscopy Congress 2016: Proceedings. Weinheim, Germany: Wiley‐VCH Verlag GmbH & Co. KGaA, 2016.
Key composition optimisation of meat processed protein source by vacuum freeze-drying technology using Linkam’s FDCS196
This study, using Linkam’s FDCS196 Freeze Drying System, shows how the freeze-drying process can be used to preserve meat and discusses the effect of system pressure on the freeze drying efficiency.
Access the application note here.
Prickett, Richelle C., et al. "Effect of supercooling and cell volume on intracellular ice formation." Cryobiology 70.2 (2015): 156-163.
Effect of supercooling and cell volume on intracellular ice formation using Linkam’s FDCS196
Studying the effect of supercooling and cell volume on intracellular ice formation (IIF), using Linkam’s Freeze Drying system the FDCS196.
Using Linkam’s FDCS196 to Investigate How Small Molecule Ice Recrystallisation Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations
Researchers at the University of Ottowa, Canada used Linkam’s Freeze Drying system, the FDCS196 to cryopreserve red blood cells with slow cooling rates prior to storage at -80°C.
Access the research paper here.
Capicciotti, C.J. et al. Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations. Sci. Rep. 5, 9692; DOI:10.1038/srep09692 (2015).
Operando micro-spectroscopy on ZSM-5 containing extrudates during the oligomerization of 1-hexene
This article studies the impact of the binder material in industrial catalysts. Using the Linkam TS1500V to perform catalytic reactions at 250 and 300°C, the authors used operando spectrocopy and in situ confocal fluoroscence microscopy to show how different binder materials affect the final material composition.
Hot stage microscopy and its applications in pharmaceutical characterisation
THMS600 and DSC450 shown above
Find out here about how hot stage microscopy (HSM) and Differential Scanning Calorimetry (DSC) can be used for pharmaceutical applications.
Choose Linkam’s THMS600, for hot stage microscopy, or our DSC450 for optical differential scanning microscopy.
Kumar, A., Singh, P. & Nanda, A. Hot stage microscopy and its applications in pharmaceutical characterization. Appl. Microsc. 50, 12 (2020). DOI: 10.1186/s42649-020-00032-9
Supramolecular synthesis and thermochemical investigations of pharmaceutical inorganic isoniazid salts
Using one of Linkam’s Peltier stages, research performed hot stage microscopy measurements on inorganic salts for pharmaceutical applications.
Read the full paper here (access required).
Multiple approaches to pharmaceutical polymorphism investigation.
In this work, researchers used Linkam’s LTS350 (now replaced by the LTS420) stage to characterise the physiochemical properties of a pharmaceutical solid compound in four different forms (anhydrous polymorphs (Forms I and II) and two monohydrates (Forms III and IV)) to evaluate its suitability for pharmaceutical development.
Read the full paper here (access required).
LTS420 shown above
Double-twist cylinders in liquid crystalline cholesteric blue phases observed by transmission electron microscopy
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Linkam’s FTIR600 used in research into germanium as a new catalyst for diamond synthesis, and a new optically active impurity in diamond
Researchers used Linkam’s FTIR600 stage to explore the catalytic ability of germanium for the conversion of graphite to diamond at HPHT conditions.
Linkam’s FTIR600 used in research into lead iodide perovskite light-emitting field-effect transistor
Linkam’s FTIR600 was used to show that the screening effects associated with ionic transport can be effectively eliminated by lowering the operating temperature of methylammonium lead iodide perovskite field-effect transistors.